Before you are ready to compare costs for CRM, you will need to know exactly what it is that you want your customer relationship manager software to do. There are many great CRM software solutions available; however, they are not all created equal. Once you have decided what it is that you want from your CRM software, you can begin to compare one to the other. For instance, you will need to know what the difference is between Microsoft CRM and Salesforce.com. Microsoft CRM vs Salesforce Platforms. Both of these CRM services are built using relational database platforms. These systems both have their advantages and disadvantages. They can both be great for your company, but you will need to know what features each system can offer you. You should not only be able to get help with contact management, but you should also be able to use these systems for separate lead, account and opportunity management. You can also use features such as complex scheduling, service management and more with both of these systems.